Pharmacological Versatility of N-Acetylcysteine: A Comprehensive Review of its Antioxidant and Therapeutic Applications
N-acetylcysteine (NAC) is a widely recognized medicine and essential drug, primarily used as an antidote for acetaminophen overdose and as a mucolytic agent for respiratory conditions. Its significant clinical interest stems from its remarkable capacity to elevate intracellular glutathione levels, acting as a potent antioxidant and anti-inflammatory compound crucial for maintaining cellular redox balance and treating diseases linked to oxidative stress.
NAC’s therapeutic potential spans diverse conditions, including chronic obstructive pulmonary disease (COPD), certain psychiatric conditions, and kidney protection from contrast dyes. Ongoing research continues to explore its efficacy in managing flu symptoms, reducing homocysteine levels, and addressing drug-resistant infections, solidifying its place as a cornerstone compound in critical and chronic care settings.